Intraindividual Stability of Human Erythrocyte Cholinesterase Activity

Intraindividual stability of human erythrocyte cholinesterase activity.

BACKGROUND Erythrocyte cholinesterase (RBC-ChE) activities serve as useful and sensitive biomarkers to monitor exposure to cholinesterase-inhibiting substances, such as chemical warfare nerve agents and pesticides. Although the interindividual variation of RBC-ChE is well characterized, the magnitude of intraindividual variation for RBC-ChE remains controversial. An accurate measure of intraind...

Relationship of erythrocyte cholinesterase activity to cell metabolism.

The Clinical Stability of Serum Cholinesterase Activity.

Intra-individual variation of serum cholinesterase activity as determined in 82 normal adults studied 373 times over periods up to 5 years is found to be relatively low. The over-all coefficient of variation was 8.4, the linear correlation between the first and subsequent tests in the same person was r = .87 (first versus second test in 82 subjects) and r = .90 (first versus seventh test in 14 ...

The mode of recovery of cholinesterase activity in vivo after organophosphorus poisoning. 1. Erythrocyte cholinesterase.

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Erythrocyte cholinesterase activity levels in desert farm workers.

In this study we have examined 532 migrant farm workers engaged mainly in the cultivation of vegetable crops, in both greenhouses and openfarms, and an equal number of controls. Erythrocyte acetylcholinesterase activity (AChE) was measured to determine the degree of toxicity due to exposure to organophosphate and carbamate pesticides in the farm workers employed either as foremen (41.5%) or far...